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The air-jet loom is widely used in the textile industry and the main nozzle is one of its key components. In this paper, the influence of some parameters, including the input air pressure and the structure of nozzle core and its internal diameter, on the internal flow field of the main nozzle is analyzed. Then the optimized structure of the main nozzle is proposed from the perspective of fluid dynamics. In the present simulations, the realizable [Formula: see text] model is applied to model the internal flow field of the main nozzle. The results show that the velocity in the annular throat reaches supersonic. Moreover, the pressure at the end of the nozzle core is the lowest in the main nozzle. It is also shown that the input air pressure has little effect on the axis velocity in Zone B, but on the other hand, has a great influence on the near-wall velocity field and the axis velocity in Zone C. In addition, an optimized structure of the nozzle core is proposed in this paper. It is found that with the proposed structure, the velocity boundary layer near the wall of Zone B in the accelerating tube can be well improved, and rapid diffusion of airflow in this area can be avoided. These help increase the moving speed of the weft yarn. Last but not least, we also show that decreasing of the internal diameter of the nozzle core improves the axis velocity of the weft accelerating tube. However, it brings a stronger turbulence at the same time.

Centrifugal pumps as turbines (PATs) are widely used in chemical engineering for recycling the abundant energy from high-pressure fluid. The operation of PATs is significantly affected by their upstream conditions, which are not steady (i.e., with a constant flow rate) in reality, thus, research on the flow mechanism of PATs under transient conditions should be considered of higher importance. In this study, a numerical model of a PAT was developed by employing the sliding mesh method to describe turbine rotation, and a user-defined function (UDF) for characterizing transient flow conditions. Corresponding experiments were also conducted to provide validation results for the simulation, and the simulation results agreed well with the experimental outcomes. The instantaneous characteristic curves under the current working conditions were obtained for different transient flow rates. The results show that the turbine’s efficiency is significantly affected by transient flow conditions. In particular, a rapid increase (large time derivative) of flow rate results in a large energy dissipation at the turbine outlet, and therefore, the turbine efficiency decreases. In addition, as the flow rate increases, the hydrodynamic force on the impeller, and the pressure fluctuation amplitude in the volute first decrease and then increase, reaching the minimum near the design flow rate. The current study provides a reliable and precise approach for the estimation of hydrodynamic performance of fluid machinery under transient flow conditions.

Cancer is an important factor threatening human life and health; in recent years, its morbidity and mortality remain high and demosntrate an upward trend. It is of great significance to study its pathogenesis and targeted therapy. As the complex mechanisms of epigenetic modification has been increasingly discovered, they are more closely related to the occurrence and development of cancer. As a reversible response, epigenetic modification is of great significance for the improvement of classical therapeutic measures and the discovery of new therapeutic targets. It has become a research focusto explore the multi-level mechanisms of RNA, DNA31, chromatin and proteins. As an important means of cancer treatment, radiotherapy has made great progress in technology, methods, means and targeted sensitization after years of rapid development, and even research on radiotherapy based on epigenetic modification is rampant. A series of epigenetic effects of radiation on DNA methylation, histone modification, chromosome remodeling, RNA modification and non-coding RNA during radiotherapy affects therapeutic effects and prognosis. Starting from the epigenetic mechanism of tumorigenesis, this paper reviews the latest progress in the mechanism of interaction between epigenetic modification and cancer radiotherapy and briefly introduces the main types, mechanisms and applications of epigenetic modifiers used for radiotherapy sensitization in order to explore a more individual and dynamic approach of cancer treatment based on epigenetic mechanism. This study strives to make a modest contribution to the progress of human disease research.