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Cancer is a global health issue that is rising swiftly with younger people and an increased number of patients. The role of human microbiota in the pathophysiology of tumors has been paid more and more attention. Microecologics including prebiotics, probiotics, and synbiotics are among the best validated/proven resources for the application of microbiological prophylaxis and therapy. There is strong evidence that microecologics have anti-cancer activity and their potential association with cancer is significant. In this review, we will focus on the role of prebiotics, probiotics, and synbiotics in tumor suppression in maintaining the colon barrier, metabolism, immune regulation, inhibition of host tumor cell proliferation, and epidemiologicalbased recommendations. Besides, other signs illuminate the role of microecological agents to adjunct the cancer treatment and counter the toxic side effects of cancer drugs. In addition, we will explore their role in chemotherapy, where these probiotics can be used as an adjunct to chemotherapy, counteracting the toxic side effects of chemotherapy drugs to minimize or optimize the therapeutic effect. In the treatment of cancer, we can see the role of prebiotics, probiotics, synbiotics, and their application in cancer patients, and the effectiveness effect can be considered as a clinical benefit. Practical applicationsA large number of studies have shown that microecologics including prebiotics, probiotics, and synbiotics play an important role in regulating intestinal microecology and contribute to the prevention and treatment of cancer, indicating that prebiotics, probiotics, and synbiotics have the potential to be used as microecological modulators in the adjuvant therapy of cancer. However, it is not clear what is the anti-tumor mechanism of these microecologics and how they antagonize the side effects of cancer chemotherapy and protect normal cells. This paper reviews the role of prebiotics, probiotics, and synbiotics in tumor suppression in maintaining the colon barrier, metabolism, immune regulation, and prevention of rapid growth of host cells, as well as their potential role in cancer chemotherapy. This review helps to better understand the relationship between prebiotics, probiotics, and synbiotics with immune regulation, intestinal microecology, metabolic regulation, and cell proliferation and provides strong evidence for their potential application as microecologics in cancer adjuvant therapy.

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Islam is a humanity based religion and unity plays of a vital role in it. It is not possible for a humane person to deny the importance of unity for a better society. It is the one thing that leads the nations of the world in the way of progress and prosperity. On the other hand chaos and anarchy is such a curse that makes a nation fall into the depths of disgrace. No enemy needs to fight such nation to defeat it. Their own internal conflicts and chaos is enough to dismantle them. Unfortunately this egoism and prejudice has reached its climax among the Muslims of Pakistan. We have failed ourselves in building a balanced progressive and welfare society based on two nation theory. Witnessing this situation many scholars from different schools of thoughts have tried their best towards the progress of inter-Muslim harmony and tolerance. In this regard they have highlighted the evil effects of chaos and positivity of unity. They have also brought forward such advises both in speech and written through which damage caused by sectarianism can be handled.