IntroductionAdults with end-stage kidney disease (ESKD) treated with haemodialysis experience mortality of between 15% and 20% each year. Effective interventions that improve health outcomes for long-term dialysis patients remain unproven. Novel and testable determinants of health in dialysis are needed. Nutrition and dietary patterns are potential factors influencing health in other health settings that warrant exploration in multinational studies in men and women treated with dialysis. We report the protocol of the “DIETary intake, death and hospitalisation in adults with end-stage kidney disease treated with HaemoDialysis (DIET-HD) study,” a multinational prospective cohort study. DIET-HD will describe associations of nutrition and dietary patterns with major health outcomes for adults treated with dialysis in several countries.Methods and analysisDIET-HD will recruit approximately 10 000 adults who have ESKD treated by clinics administered by a single dialysis provider in Argentina, France, Germany, Hungary, Italy, Poland, Portugal, Romania, Spain, Sweden and Turkey. Recruitment will take place between March 2014 and June 2015. The study has currently recruited 8000 participants who have completed baseline data. Nutritional intake and dietary patterns will be measured using the Global Allergy and Asthma European Network (GA2LEN) food frequency questionnaire. The primary dietary exposures will be n-3 and n-6 polyunsaturated fatty acid consumption. The primary outcome will be cardiovascular mortality and secondary outcomes will be all-cause mortality, infection-related mortality and hospitalisation.Ethics and disseminationThe study is approved by the relevant Ethics Committees in participating countries. All participants will provide written informed consent and be free to withdraw their data at any time. The findings of the study will be disseminated through peer-reviewed journals, conference presentations and to participants via regular newsletters. We expect that the DIET-HD study will inform large pragmatic trials of nutrition or dietary interventions in the setting of advanced kidney disease.

Rationale & Objective: Clinical practice guidelines for dietary intake in hemodialysis focus on individual nutrients. Little is known about associations of dietary patterns with survival. We evaluated the associations of dietary patterns with cardiovascular and all-cause mortality among adults treated by hemodialysis.

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ezenterik ven trombozu (MVT) nadir görülen bir akut batın nedeni olup, tüm akut mezenter iskemisi olgularının %5-15'ini oluş-turmaktadır.1 Altta yatan predispozan faktörün bulunamadığı primer MVT ve etiyolojinin saptanabildiği sekonder MVT olarak ikiye ayrılır. Sekonder nedenler arasında, hiperkoagülabilite yaratan, geçirilmiş abdominal cerrahi, malignite varlığı, miyeloproliferatif hastalıklar, oral kontraseptif gibi bazı ilaçların kullanımı, protein S ve C eksiklikleri, antitrombin 3 eksikliği, protrombin ve faktör V Leiden mutasyonu gibi sebepler sayılabilir. Hastalık genellikle nonspesifik abdominal ağrı ile başlar ve takiben progresif olarak artan ağrıya, bulantı, kusma, kanlı diyare ve daha Turkiye Klinikleri J Med Sci 2012;32(5)

Free-floating thrombus (FFT) of the carotid artery is an exceptional medical condition with a currently unclarified pathophysiology. Approximately 150 cases have been described and published in the literature throughout the world so far. Thus, no definite management strategies have been established yet. In this paper, a symptomatic case of an FFT inside the common carotid artery (CCA) presented with a history of slurred speech, and right sided hemiplegia was reported. After the diagnosis of a mobile thrombus within the origin of the left CCA, the patient was placed on anticoagulation. As the medical therapy failed, carotid thromboendarterectomy was performed.