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We investigated exercise induced urinary albuminThe three groups did not differ in 24 h UAE. Exercise excretion rate (UAE) (ex-UAE) in patients with borderline induced a significant increase in UAE only in BH. Exerhypertension (

Previous studies have shown that the QT/QS(2) ratio is increased during adrenergic stimulation and may be abnormal in patients with high adrenergic tone. The purpose of this study was to assess the QT/QS(2) ratio as an index of cardiac adrenergic tone in 19 patients with mitral valve prolapse syndrome, in 16 patients with hyperthyroidism, in 20 patients with borderline hypertension and to compare with age- and sex-matched control subjects. Resting phonocardiograms and electrocardiograms were recorded and the following parameters were analyzed: heart rate, electrical systole (QT interval), electromechanical systole (QS(2) interval), and QT/QS(2) ratio. The QT/QS(2) ratio values were increased in patients with mitral valve prolapse syndrome and in patients with hyperthyroidism when compared with control groups. A significant positive correlation (r = 0.63) was found between the QT/QS(2) ratio and plasma thyroxine levels in patients with hyperthyroidism. No differences were found between patients with borderline hypertension and their controls. We conclude that increased QT/QS(2) ratio in patients with mitral valve prolapse syndrome and in patients with hyperthyroidism confirms the hypothesis of enhanced cardiac adrenergic tone in these patients.

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