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Abstract. The deep crustal temperatures of the Northern Tien Shan region are being calculated on the basis of direct measurements of the heat flow and empirical relation of geothermal parameters and seismic velocities. For this purpose the applied method of numerical solution of conductive heat transfer equation takes into account additional sources of heat release due to radioactive decay. Thermoelastic deformations, reaching 20-40% of the total lithostatic pressure at depths of 35-60 km, are determined. The criteria controlling the distribution of hypocenters of earthquakes have been determined in accordance with the morphology of the regions of excess temperatures and thermal stresses.