This research is motivated by the low interest and motivation of students to learn mathematics in the third grade of SDN 19 Nan Sabaris. The purpose of this study was to see the effect of Ludo media to increase the interest and motivation of mathematics learning in third grade students of SDN 19 Nan Sabaris. This type of research is quasi-experimental with a sample of all third grade students of SDN 19 Nan Sabaris registered in the 2018/2019 school year. The research instrument used was in the form of a questionnaire to see motivation and student learning interest in mathematics in grade III of SDN 19 Nan Sabaris. The data analysis technique used is paired-sample t-test. The results of data analysis showed that there were significant differences in the results of interest in and motivation to learn mathematics in third grade students at SDN 19 Nan Sabaris. This means that the use of ludo game media can significantly increase students’ interest and motivation in learning about Mathematics.