The landscape of software engineering is evolving rapidly amidst the digital transformation and the ascendancy of AI, leading to profound shifts in the role and responsibilities of software engineers. This evolution encompasses both immediate changes, such as the adoption of Language Model-based approaches in coding, and deeper shifts driven by the profound societal and environmental impacts of technology. Despite the urgency, there persists a lag in adapting to these evolving roles. By fostering ongoing discourse and reflection on Software Engineers role and responsibilities, this vision paper seeks to cultivate a new generation of software engineers equipped to navigate the complexities and ethical considerations inherent in their evolving profession. CCS CONCEPTS• Software and its engineering → Software creation and management; • Social and professional topics → Computing education; Codes of ethics.
The role of viruses has been studied extensively for use as curative cancer therapies. However, the natural immunogenicity of viruses and their interaction with the host’s immune system needs to be examined to determine the full effectiveness of the viral treatment. The prevalence of cancer is increasing globally, and treatments are needed to support the increasing body of patient care. Oncolytic viral therapies used existing pathogenic viruses, which are genetically modified to not cause disease in humans when administered using a vaccine viral vector. Immunotherapies are another avenue of recent interest that has gained much traction. This review will discuss oncolytic viral approaches using three DNA-based viruses, including herpes simplex virus (HSV), vaccinia virus, and adenovirus; as well as four RNA-based viruses, including reovirus, Newcastle disease virus (NDV), poliovirus, and measles virus (MV). It also examines the novel field of cancer-based immunotherapies.
Osteoporosis is a disease of the bone characterized by a loss in bone mineral density. Although this disease is commonly diagnosed in adults, it is not directly associated with increasing age. There are many links and potential risk factors to developing osteoporosis, including hormonal imbalances, nutrient deficiency, cardiovascular health, and exercise. This review examines how osteoporotic fractures are diagnosed using bone imaging techniques, including dual-energy X-ray absorptiometry scans. The quality of life for patients with osteoporosis is discussed concerning the protective and risk factors associated with osteoporosis. Specifically, the risk factors for osteoporosis include genetic inheritance patterns, BMI, age, and lifestyle choices (including alcohol consumption, smoking, and physical exercise). There are many protective factors for preventing osteoporotic fractures, including natural bone supplements and prebiotics. These supplements can be found in most dairy products, which are fortified with vitamin D, which can be consumed in the diet to support bone health. Prebiotics can also be used to increase the healthy proliferation of commensal gut bacteria that are used to improve the bone-building process, relieving bone breakdown during the stages of bone turnover. These therapeutic interventions can be applied to support existing patient care to prevent and maintain overall bone health.
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