Purpose The purpose of this paper is to identify the factors influencing community participation in destination building and its consequences for the local inhabitants in the form of social, tourism and economic development. Design/methodology/approach Data for this study was collected from 214 questionnaires from residents of different tourist destinations in the Poonch district of J&K. This study used explorative factor analysis, confirmatory factor analysis and structural equation modeling techniques for determining the structural estimates between constructs. Findings The results revealed that the personal and economic factors have the most significant impact followed by the social factor and least by the environmental factor upon the local community participation. Moreover, the respondents agreed that destination development has contributed a lot in terms of economic and followed by other two factors. Originality/value The study makes a significant theoretical contribution to the community-based tourism literature by portraying the influence of various factors on community participation and its repercussions and, moreover, the study has used the social exchange theory with a different area. Furthermore, the study has made a number of practical implications for the local authority for sustainable tourism as well as community development.

The genetics of coat color variation remains a classic area. Earlier studies have focused on a limited number of genes involved in color determination; however, the complete set of trait determinants are still not well known. In this study, we used high-throughput sequencing technology to identify and characterize intricate interactions between genes that cause complex coat color variation in Changthangi Pashmina goats, producer of finest and costly commercial animal fiber. We systematically identified differentially expressed mRNAs and lncRNAs from black, brown and white Pashmina goat skin samples by using RNA-sequencing technique. A pairwise comparison of black, white and brown skin samples yielded 2479 significantly dysregulated genes (2422 mRNA and 57 lncRNAs). Differentially expressed genes were enriched in melanin biosynthesis, melanocyte differentiation, developmental pigmentation, melanosome transport activities GO terms. Our analysis suggested the potential role of lncRNAs on color coding mRNAs in cis and trans configuration. We have also developed online data repository as a component of the study to provide a central location for data access, visualization and interpretation accessible through http://pcd.skuastk.org/ .

Purpose Quality use of antibiotics and the development of antibiotic resistance is a global catastrophe. In the conceptual context, the phenomenon is correlated with the healthcare practitioners’ understanding of antibiotic use and resistance. Therefore, the study aimed to highlight nurses’ perception of antibiotic use and resistance at a public healthcare institute in Quetta City, Pakistan. Respondents and Methods By using a semi-structured interview guide through the phenomenology-based approach, in-depth, face-to-face interviews were conducted. Nurses practicing at the surgical and medical units of Sandeman Provincial Hospital (SPH), Quetta, were approached for the study. All interviews were audio-taped, transcribed verbatim, and were then analyzed for thematic contents by the standard content analysis framework. Results Although the saturation was reached after the 13th interview, an additional two were interviewed for absolute validation. Content analysis revealed five major themes: (1) defining antibiotics and antibiotic resistance, (2) antibiotic use: awareness and concern, (3) antimicrobial resistance: awareness and concern, (4) responding to antibiotic use and resistance, and (5) barriers to quality use of antibiotics and prevention of antibiotic resistance. Even though the understanding of nurses regarding antibiotic use and resistance was promising, certain apprehensions were also observed. The respondents were aware of the critical situation and provided valuable insights that can offer significant input while promoting the quality use of antibiotics in a developing country. Conclusion While the perception towards antibiotics appeared positive, potential areas of concern and contributing factors regarding antibiotic resistance were also identified. Importantly, nurses too highlighted possible solutions to address the issue of irrational antibiotic use and the development of antibiotic resistance.

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In current research the structural, optoelectronic, elastic, and thermoelectric properties of NaMF3 (M = Si and Ge) ternary perovskites (Halide Perovskites) compounds using first-principle modeling are computed within the DFT framework. The obtained results of phonons dispersion curves and the tolerance factor is calculated for NaSiF3 and NaGeF3 and is found to be 1.001 and 1.004 respectively, which reveals that these compounds are structurally and thermodynamically stable in cubic phase. The elastic constants and other parameters demonstrates that these compounds are mechanically stable, hard to scratch, ductile, anisotropic and possesses resistance to plastic distortion. The band structure and density of states (DOS) demonstrate the semiconducting nature for the NaSiF3 and NaGeF3 compounds with direct band gap of 1.15 eV and 3.31 eV respectively from “R-R” symmetries points. The optical properties are investigated and it is observed that the selected compounds possess strong optical conduction and absorption coefficient and are transparent at low incident photons energy ranges and led us to the conclusion that for high frequency UV device these compounds possesses suitable applications. The thermoelectric properties indicate that both the materials possesses notable power factor and figure of merit (ZT), due to which its applications in solar cells can be deemed. To our knowledge, this is first NaMF3 (M= Si and Ge) theoretical computational systematic study of structural, optoelectronic, elastic, and thermoelectric properties which will experimentally validated. Our findings add comprehensive insight in predicting fabricating high performance hetero-junction solar cells.