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Despite the World Health Organization's declaration that the COVID-19 global emergency has ended, the threat of future pandemics remains a significant concern. This paper highlights the potential role of Artificial Intelligence (AI) in strengthening global health systems and mitigating future health crises. We discuss AI's proven utility throughout the COVID-19 pandemic, including disease surveillance, diagnostics, and drug discovery. AI's ability to rapidly analyze vast amounts of data to derive accurate trends and predictions underscores its superiority over traditional computer technology. However, the effective and ethical implementation of AI encounters significant challenges, including a pronounced digital divide, with applications mainly concentrated in high-income countries, thus exacerbating health inequities. We argue for international cooperation to enhance digital infrastructure in low- and middle-income countries, tailoring AI solutions to local needs, and addressing ethical and regulatory issues. The importance of maintaining evidence-based practice, rigorous evaluation of AI's impact, and investment in AI education and innovation are stressed. Ultimately, the potential of AI in global health systems is clear, and tackling these challenges will ensure its robust contribution to global health equity and resilience against future health crises.

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