No abstract

The incidence of perioperative cardiac events is higher in patients with abnormal MPI. Dipyridamole 99m Tc-MIBI myocardial perfusion imaging can accurately detect the preoperative cardiac risk of patients undergoing major non-cardiac surgery. Based on these findings, the occurrence of perioperative cardiac events in patients with abnormal MPI should be considered, especially in the older age population (age ≥70).

Animal and human studies indicated that overtension and stress release inflammatory substances and growth factors that are produced following exercise, which leads to satellite cell activation and proliferation. The aim of the present study was to investigate the effect of an 8-week endurance exercise and estrogen supplementation on the proliferation of satellite cells in rats. Seventy-six rats were selected and randomly divided into two equal groups, ovariectomized and intact groups. Both groups were randomly divided into four subgroups as follows: endurance exercise, estrogen supplementation, estrogen supplementation with endurance exercise, and control. Then, the endurance exercise group and estrogen supplementation with endurance exercise group performed endurance exercise for 8 weeks, three sessions per week. In each week, the estrogen supplementation group and estrogen supplementation with endurance exercise group were injected subcutaneously with 3 mg/kg of estradiol benzoate.The soleus muscle was retracted and placed into 10 % buffered formalin solution. In a pathological lab, the number of satellite cells was counted and recorded using a light microscope through hematoxylin and eosin staining and immunohistochemistry for CD56. Increase in satellite cell number was significant in the two groups of intact rats treated with estrogen supplementation and the ovariectomized rats which performed endurance exercise. The comparison of these groups' means demonstrated that the satellite cell number increased more in the ovariectomized rats. Endurance exercise and estrogen supplementation can increase the proliferation of satellite cells in the rat's soleus muscle.

Patients with DTC with pulmonary metastasis have a relatively favorable prognosis and response rate, as well as longer survival. The type of DTC is the only factor that affects the response to treatment.

Radioiodine ((131)I iodide) has long been a safe, effective and widely used treatment in the management of differentiated thyroid cancer (DTC). Concerns regarding stochastic radiogenic risks have led to regulatory criteria for the release from medical confinement of patients who receive such radionuclide therapy. Over a 6-y period, the external whole-body dose rates at 1 m from 562 DTC patients were measured with an ionisation chamber calibrated in microsieverts per hour out to 5-d post-administration. Patients were stratified into four administered activity groups: 3.7 GBq (36.8 %), 5.55 GBq (47.3 %), 7.4 GBq (12.8 %) and 9.25 GBq (3 %). Consistent with previously published data, the current study demonstrated that a bi-phasic model accurately described (131)I-iodide kinetics up to at least 5-d post-administration in DTC patients, providing data that would be useful in formulating radiation safety guidelines for staff and other individuals coming into contact with such patients after treatment.