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Objective: COVID-19 prevalence is a new and serious threat to public health. The disease has had an impact on nearly every important economic, political, social, and even military aspect of many countries around the world. As a result, the psychological effects of this viral disease on different levels of society's psychological health are critical, necessitating scientific research. This study looked into the possible link between COVID-19 and psychological distress and anxiety in Iran. Methods:The first large-scale global study of psychological distress and anxiety in public society, this crosssectional (descriptive-analytical) study was based on the participation of people from some Asian countries during the COVID-19 epidemic. Only the results from Iran were presented in this article. This study had 1480 participants and used a standard questionnaire called the COVID-19 Peritraumatic Distress Index (CPDI) with a Cronbach's alpha of 0.82. Results:It was discovered that 1171 (79%) of the participants were female, while 309 (21%) were male. The CPDI Questionnaire yielded a mean score of 54.16±6.13. There was a significant relationship (p=0.0002) between age group and total score of psychological distress and anxiety. The findings revealed a link between anxiety variables and education (p = 0.0001), monthly income (p = 0.008), and gender (p = 0.019). Conclusion:It can be concluded that many study participants were in an unfavorable psychological distress and anxiety situation.

Background and aims: Multiple sclerosis (MS) is a common neurological disorder with complex etiology, which is highly affected by psychological factors. These factors should to be identified to help patients with MS (PwMS). This study aimed to compare coping styles, personality traits, and resiliency in PwMS and healthy subjects. Methods: In this case-control study, we selected 75 PwMS from the members of Tehran MS Society in 2016 as case group and 75 healthy subjects as control group. To collect data, we used the Ways of Coping Questionnaire (WOCQ), Big Five Factor Inventory–Revised, and Conner-Davidson Resilience Scale (CD-RISC). Multivariate analysis of variance (MANOVA) and independent T-Test were used to analyze the data. Results: The results indicated that PwMS use emotion-focused coping styles more often (44.53±9.13, P=0.008) and problem-focused coping styles less often (39.84±5.79, P=0.001) compared to control group. Also, they showed higher scores in neuroticism (32.10±4.80, P=0.001) and lower scores in extraversion and conscientiousness (27.46±7.12, P=0.005 and 32.98+±5.72, P=0.008, respectively). The resiliency levels in these patients were also lower than healthy subjects (68.13±13.90, P=0.021). Conclusion: Our findings indicated that PwMS are more likely to use emotional coping strategies in stressful situations compared to healthy individuals. Moreover, data confirmed that a maladaptive personality configuration, which is specified by high neuroticism, along with low extraversion, conscientiousness, and agreeableness are somehow related to MS.

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