Objectives Inborn errors of immunity (IEIs) are monogenic diseases of the immune system. Despite the increasing genetic advancements, the diagnosis of IEIs still lean on clinical diagnosis. Dermatological manifestations are observed in a large number of IEI patients and can lead to proper approach and prompt intervention. Methods This cross‐sectional study was carried out between 2018 and 2020 on IEIs at a Children's tertiary care center in Tehran, Iran. Demographic details and age at onset of symptoms of IEI were recorded. Results Overall, 212 patients were included. Cutaneous findings were reported in 95 (44.8%) patients, and 61 of 95 (64.2%) reported skin lesions as the first clinical presentation. Skin infection (69, 72.6%) was the most frequent cutaneous manifestation, followed by eczematous rash (24, 25%). Conclusions Skin manifestations are a common feature in IEI patients and are readily recognizable by healthcare providers. This study tried to provide information on prognostic consequences.

There is no robust consensus on whether the more oblique femoral tunnel position offers better results than standard surgical technique in term of operative outcomes. Thus, it is important to determine the thorough position of the femoral tunnels. This study investigated whether a change in the femoral tunnel position in both axial and coronal planes can significantly alter the postoperative functional and clinical outcomes of the patients. Method: This comparative, retrospective, single-center study was performed on 44 patients who had underwent singlebundle Anterior Cruciate Ligament Reconstruction (ACLR). To evaluate the tunnel position in coronal and axial planes, radiographic assessments were done. Based on radiographic data, the patients were classified into 4 groups. The time interval between surgery and last visit averaged 23.6 ± 2.2 months (18-30 mos.). Lysholm knee score, and Cincinnati score were completed for all of the patients. Furthermore, the Lachman, anterior drawer and pivot-shift tests were performed. Results: Of the 44 patients included in the study, 9 patients (20.4%) were classified as the low-anterior group, 17(38.6%) were classified as the lowposterior group and 18(40.9%) were classified as the high-posterior group. None of the patients were included in high-anterior group. A greater mean Lysholm score (96±3) in low-posterior group was the only significant difference between the three groups. Conclusion: Findings of the current study show that with the low-posterior placement of the femoral tunnel, based on both anteroposterior (AP) and tunnel-view x-rays, the better clinical outcomes can be achieved in short-term than the routine tunnel placements