Purpose: The present study was conducted to evaluate the effect of topically applied Nigella Sativa (Black Seeds) on osseointegration of delayed dental implant in an effort to improve outcomes of dental implants. Subjects and Methods: The current study was performed on twelve (12) healthy patients that were divided randomly into two groups: Group 1 (Test group) included six (6) patients with delayed implant insertion with the topical use of nigella sativa; Group 2 (Control group) included six (6) patients with delayed implant insertion without the use of nigella sativa. Results: A non-statistically significant difference was recorded in clinical parameters after three and six months follow up in both groups. Test group showed a highly significant increase in its bone density after six months in comparison with control group. Conclusion: The topical use of nigella sativa in delayed dental implant showed an improvement in peri-implant tissues. INTRODUCTION Dental implant is a valuable management approach in complete or partially edentulous patients, playing an important role in orofacial anatomic contour reconstruction, health, function, and esthetic (1,2) .
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