The purpose of this study was to explore the levels of role related stress and burnout among the nurses working in the private hospitals. Furthermore, the study also examined the relationship between role related stressors and burnout. The Maslach Burnout Inventory (MBA-HSS) and the Occupational Stress Inventory (revised edition) were used to measure burnout and role related stress. The mean scores are indicating a moderate level of stress and burnout among the nurses working in the private hospitals. Role related stressors were significantly related to all burnout dimensions. The results of regression analysis reveal that role overload and role insufficient were significant predictors of emotional exhaustion. Role overload, role insufficient and role ambiguity were found to be significant predictors of depersonalization. The significant predictors of personal accomplishment were role insufficient, role ambiguity and role boundary.