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The current study included 5 ml blood were collected from 100 patients with asthma and 100 controls. Who admitted to Hila General teaching hospital and margin hospital through the period from October 2017 to April 2018.The study deals with detection of cytokines concentration IL-18 showed increased at in concentration especially in age group (12-21 years) years and reached reach 314.777 pg/ml compared to control group. HSP70 showed increase in their concentrations in asthma patient than in controls especially at age group (12-21 years) years which reached 117pg/ml.The patient samples were applied to determine some parameters include (Hb, RBC count, WBC & Eosinophil count) .The results revealed that the mean Hb and RBC levels for asthmatic patients were lower than control (8.5000±4.65855g/dL, 10.9979 ±4.09533g/dL. 6.5000±4.07999310x12/l, 3.5183±6.0721610x12/L) respectively. In this study the patients suffered from Iron deficiency anemia and nutritional deficiency. While leukocyte and Eosinophile count values were higher than normal (8.5000±4.65855g/dl , 10.9979±4.09533g/dl).