No abstract

No abstract

Introduction: Acute coronary syndrome mainly occurs as a result of plaque rupture of atherosclerosis. Apolipoprotein B (apoB) is a large glycoprotein, playing a role in lipoprotein metabolism and human lipid transport reflecting the number of circulating atherogenic particles. The purpose of this study was to assess the relationship of serum apoB levels with coronary lesion severity. Method: This is a cross-sectional study involving patients who was diagnosed with Non-ST Elevation Myocardial Infarction (NSTEMI) who underwent coronary angiography in November 2021 to July 2022. The NSTEMI criteria follow the Universal Definition of Myocardial Infarction and coronary severity is assessed using a SYNTAX score. Bivariate analysis was conducted looking for the relationship between apoB with SYNTAX scores with p<0.05 considered statistically significant. Results: The subjects of the study is 70 people, dominated by male 50 patients (71.4%). The median age of the subjects was 56 (38-77) years. Median levels of apoB was 107 (32-150) mg/dL. The average SYNTAX score was 25.66 ± 10.83. Using the Pearson correlation test, it was shown that there is a significant correlation between apoB and coronary lesion severity obtained r=0.442 (p<0.001). Conclusion: There is a significant correlation between apoB and coronary lesion severity using SYNTAX scores in NSTEMI patients.

The Background : Mortality rate of heart failure patients are increasing even they have a good treatment. Therefore, it should be possible to make a prognostic for chronic heart failure patients with use an easy parameter namely predice score. The aim of the study : To assess the ability of the predice score to predict mortality within 30 days in patients with chronic heart failure. The Method : We did this prospective research started from 1st July 2016 until 31st December 2016 with concerned chronic heart failure patients as many as 44 patients. We counted the association grade with use Man whitney U. The Result : The results showed that there was a signicant relationship between predice score and mortality (p = 0.004). The mean predice score in the living subjects was 11.77 (SD: 4.07) Meanwhile, the mean predice score of the subjects who died was 17.18 ( SD:2,85). The Conclusion: Predice Score can be used to predict 30-day mortality in chronic heart failure patients who experience worsening because it is statistically signicant (p<0,05).