A prevailing hierarchical structure in industrial process optimization and control includes three levels, i.e., a real time optimization (RTO) level, a double layered model predictive control (MPC) level (which is composed of a steady-state target calculation (SSTC) layer and a dynamic control layer), and a distributed control level. In this paper, a multi priority rank RTO algorithm, in which a new variable is introduced to uniformly express the set points, is presented to get optimal set points according to their importance levels. In order to guarantee the feasibility of the dynamic control layer during tracking the steady-state targets calculated in SSTC layer, the region of attraction is added into the SSTC layer as additional constraints, hence, the steady-state targets can be calculated online and transmitted to the dynamic control layer at each instant to guide the state to achieve the steady-state state gradually. The effect of the above methods are illustrated through an example.
Lecanicillones A–C (1–3), three unusual dimeric spiciferones with a cyclobutane ringvia[2 + 2] cycloaddition, were isolated from an entomopathogenic fungusLecanicilliumsp. PR-M-3.
Two new indole-diterpenoids 4b-deoxy-1'-O-acetylpaxilline (1) and 4b-deoxypenijanthine A (2) were isolated from the fermentation broth and the mycelia of the soil fungus Penicillium sp. CM-7, along with three known structurally related compounds, 1'-O-acetylpaxilline (3), paspaline (4) and 3-deoxo-4b-deoxypaxilline (5). The structures of compounds 1 and 2 were elucidated by extensive spectroscopic methods, especially 2D NMR, and their absolute configurations were suggested on the basis of the circular dichroism spectral analysis and the NOESY data.
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