Microdeletion of the short arm of chromosome 18 is one of the most common chromosome deletion syndromes. Its estimated frequency is 1 in 50,000 live-born infants, with female prevalence over males. Around 150 cases have been described till now. The reported abnormalities include growth deficiency, hypotonia, microcephaly, dysmorphic facial features such as ptosis, epicanthal folds, hypertelorism and micrognathia, and relatively small hands and feet. Our patient was a full-term low birth weight (2150 gm) female newborn, showing cleft upper lip and palate (hard and soft palate), bilateral congenital Talipes Equinovarus with rocker bottom foot, microcephaly, atrial septal defect. She was initially conservatively managed with gavage feeding, then shifted into paladai feeding of expressed breast milk. A multidisciplinary approach was adopted due to various malformations and for the potential occurring complications. To our knowledge, this is the first case diagnosed during the neonatal period.

Pulmonary abscess is defined as lung infection that destroys the lung parenchyma, resulting in cavitation and central necrosis, can result in localised area composed of thick-walled purulent material.[1] It can be either primary or secondary. Here we present a case of a 3 year old female child who presented to our hospital with complaints of fever, cough, cold, vomiting and decreased oral intake for 10 days. Lab tests revealed neutrophilic leucocytosis and raised inflammatory markers. Chest roentgenogram and High resolution Computed Tomography of thorax were done which established the diagnosis and size of lung abscess. Injectable antibiotics in form of cephalosporin, aminoglycoside and glycopeptide group of drugs together were administered. Nosurgical intervention was needed. There was slow and steady improvement in the patient's condition. Patient was discharged after 4 weeks of injectable antibiotics followed by a course of oral antibiotics for 3 weeks to be taken at home.

No abstract