Objective: The objective of this study was to evaluate the effect of digital occlusal adjustment on the radiographic outcome and masticatory efficiency of mandibular implant-supported overdentures. AbstractConclusion: T-scan III aided significantly in the process of occlusal load distribution which resulted in less marginal bone loss, more bone density gaining around the implants and better mixing ability of the food intake which enhance the masticatory efficiency.
Simple, rapid and sensitive spectrophotometric methods were developed and validated for the microdetermination of terazosin HCl, doxazosin mesylate and pioglitazone HCl drugs in pure and pharmaceutical dosage forms. These methods are based on ion-pair formation reaction between these drugs and a chromogenic reagent Rose Bengal (RBeng). These reactions were studied under various conditions and the optimum parameters were selected. The spectrophotometric microdeterminations have been done at λ max =570 nm for terazosin HCl and pioglitazone HCl and at λ max =575 nm for doxazosin mesylate. Under proper conditions the suggested procedures were successfully applied for microdetermination of these drugs in pure and in pharmaceutical dosage forms. The values of SD, RSD, recovery %, LOD, LOQ and Sandell sensitivity refer to the high accuracy and precession of the applied procedures. The results obtained were compared with the data obtained by the official methods, referring to confidence and agreement with rose bengal procedure results. The solid drugs-reagent ion-pairs were prepared, separated and their structures were investigated using elemental analysis, FT-IR, 1 H-NMR and thermal analyses and the results confirm the structures proposed by the stoichoimetric ratio in the solution work. The biological activities of the drugs and their solid ion-pairs against some types of (G-) and (G+) bacteria and fungai were studied and compared with each other. It is found that terazosin-RBeng and pioglitazone-RBeng reaction products have antibacterial effect higher than the parent drugs, but doxazosin-RBeng reaction product has almost the same antibacterial effect of the parent drug.
Wadi Morra area is one of the most important areas targeted by the government for sustainable development. This development depends mainly on groundwater occurrences. This research aims to explore groundwater in this region, which depends on groundwater for its needs. To achieve this aim, the geoelectrical resistivity method was used, represented by Schlumberger Vertical Electrical Soundings (VESs). Seventeen VESs have been carried out with a maximum half current electrode spacing (AB/2) of 700m. The measured VESs are interpreted qualitatively and quantitatively to construct a geoelectrical model. To detect the water-bearing layers and their extensions, three geoelectric cross-sections in addition to a one-panel diagram were constructed using all the available data. Also, both true resistivity and isopach contour maps of waterbearing layers were created based on these data. The interpretation results indicate that there are five geoelectric layers (A, B, C, D, and E), two of them (C and D) are water-bearing layers. The first water-bearing layer is layer C, which represents the Nubian sandstone aquifer, and the second layer is layer D, which represents the fractured basement aquifer. These two aquifers were observed along the northern part of the Saint Catherine - Nuweiba road that dissects the Wadi Morra basin, while it is absent at the southern part of this road. It is due to the presence of a few faults. According to groundwater occurrences, the study area was divided into two zones. The first zone is zone (A) where the groundwater is present, either in the Nubian sandstone aquifer or in the fractured basement aquifer and the second zone is zone (B) where there is no groundwater at all due to the presence of basement rocks at a few depths. This research also recommends that the best places for drilling productive wells be at zone A.
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