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The mean admission rate due to relapse was significantly reduced from 24.54 ± 7.48 to 2.92 ± 4.26, P b 0.004 after establishing the MS clinic. Most patients (61%) had escalated therapy (mean duration till escalation: 7.4 years). MS specialists prescribed second line DMT for 600 patients (50.1%). Escalation therapy was significantly higher in patients who were seen by an MS specialist versus those who were seen by a general neurologist (66.6% vs 33.4%, Pb0.0. Mean EDSS at latest visit to MS clinic was less than 3 in 1039 (83.3%), from 3-4 in 59 (4.7%) and more than 4 in in 148 (12.7%). ConclusionOptimal therapy decisions for MS patients via a specialised MS clinic are associated with a significant decrease in relapse rate, disability, and hence, the economic burden of multiple sclerosis.

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