Associated with the increasing demand and supply of short life-span electrical devices, e-waste generation is rapidly increasing. This created a special business for some informal groups: dismantlers, e-waste sellers, repairers, and storekeepers. The objective of this study was to assess the awareness, management strategies, and associated influencing factors among the central role players of the e-waste-related business. A cross-sectional study was used to assess the awareness and management of 345 purposely selected e-waste workers including all those who are actively engaged in e-waste buying, selling, dismantling, storing, and transferring. A questionnaire was used to obtain the required information. The findings show that about 92% of the dismantlers, 70% of the sellers, and 55% of the repair and maintenance workers have poor awareness. The awareness level of the respondents is strongly associated with the newness of the issue ( V = 0.64) and lack of concern ( V = 0.44), and moderately associated with educational status ( V = 0.31), their lack of access to information (0.31), job type (0.28) and income level (0.26). The e-waste management among the study groups was limited to unsafe disposal (50%), unsafe storage (36%), and transfer (14%) to other users. The analysis showed that there is a statistically significant association between their job type and management systems (chi2 (6) = 139, P < .005, V = 0.45). Cramer’s V ( V = 0.45) shows a strong association between their job type and the e-waste management strategies. The awareness level of the respondents is very poor and influenced by several complex factors. During the study period, no study groups were practicing any of the proper e-waste management at all.