Background and objective:We aimed to investigate the effect of “training about the pre-analytical phase” and “technological arrangements in laboratory information systems (LISs) and tube barcoding system”, on decreasing PEs.Materials and methods:PEs in 2013 and 2014 were obtained from the LIS retrospectively in order to evaluate the effect of improvements. Ten quality indicators (QIs) described for pre-analytical phase were calculated. We compared QIs of the “improved year” with the past year. Four quality specification criteria were defined as “unacceptable”, “minimum”, “desirable” and “optimum” for each quality indicator.Results:There was a reduction in all types of PEs related to the improvement strategies. When QIs were considered as quality specifications (QSs), QI-14 (number of samples damaged in transport) and QI-16 (samples improperly stored) were “unacceptable”, QI-8 (samples lost-not received) and QI-12 (samples with insufficient sample volume) were “minimum” and QI-9 (samples collected in inappropriate container) was “desirable” in 2013; QI-10a, 10b (samples hemolyzed), 11a (samples clotted) and 13 (samples with inadequate sample-anticoagulant) were all “optimum” in 2 years.Conclusion:It was shown that continuous education on pre-analytical phase and improvements of the technological infrastructures are the main factors that will enable the control of this phase.

In order to increase the efficiency of the preanalytical process at the Public Health Laboratory (PHL) where urinalysis is performed on pregnant women admitted at primary care family health centres (FHC), our aim was to demonstrate the efficacy of preservative urine tubes in this study. The first morning urine samples of 84 pregnant women were collected into urine tubes with or without preservative. The first analysis was used as a reference. The tubes with preservative containing chlorhexidine were transported at room temperature and analysed on the 2, 6, 24, and 72 h. Tubes with or without preservative and transported according to cold-chain principles were analysed on the 2nd and 6th h. Changes in comparison to the reference tube were analysed. When the test results of the tubes with preservative and kept at room temperature were compared to those of the reference tubes, the only changes that were observed were in the leukocyte morphology. During microscopic examination of the tubes with or without preservative and transported in accordance with cold-chain principles, no differences were found except pH changes during strip tests and changes in the crystal structure. The tubes with preservative containing chlorhexidine, whose performance was tested with the aim of controlling pre-analytical variables, may be used in conditions in which transportation in accordance with cold-chain principles is impossible. Tubes without preservative were observed to be adequate in conditions in which transportation in accordance with cold-chain principles is possible within 6 h.