The progressive nature of glaucoma suggests it should be possible to detect structural changes such as retinal nerve fiber layer (RNFL) thickness loss before the condition becomes clinically apparent with visual field (VF) impairment. Therefore, the aim was to analyze RNFL thickness and VF changes in study groups with unilateral exfoliation syndrome (XFS), bilateral XFS and bilateral exfoliative glaucoma (XFG), and compare it with controls. The study included 114 subjects (228 eyes) divided into 4 groups according to the presence of exfoliation: 30 subjects with unilateral XFS (30 with clinically visible XFS and 30 fellow eyes), 24 subjects (48 eyes) with bilateral XFS, 28 (56 eyes) subjects with bilateral XFG, and control group (32 subjects). All subjects underwent VF and RNFL measurements after ophthalmologic examination. Both eyes of unilateral XFS (clinically -visible and fellow eye) showed positive correlation between Mean Defect (MD) and square root of Loss of Variance (sLV) and between MD and inferior quadrant RNFL thickness. In bilateral XFS and XFG, there was negative correlation between MD and inferior quadrant RNFL thickness. Inferior, superior and nasal quadrant RNFL thickness was lower in XFG group than in other groups. In bilateral XFS group, the inferior quadrant RNFL thickness was lower as compared with unilateral XFS group (in both eyes). The mean RNFL thickness negatively correlated with MD in bilateral XFS and XFG groups. In conclusion, structural changes before VF impairment have an important role in early detection of glaucoma in subjects at risk.

This work analyses temperature characteristics in order to identify temperature trends in Novi Sad area for the period between the years 1951-1990. The data used were obtained in meteorological stations in Rimski Šančevi and in Petrovaradin. This study presents annual mean temperatures, average values at 7, 14 and 21h, average mean maximum and minimum values and average values per different seasons, respectively. Different statistical methods (arithmetic mean, standard deviation and correlation coefficient) and formulae of vertical gradient of air temperature and thermal coefficient were applied when analyzing temperature values. On the basis of analyzed and given results, it can be concluded that Novi Sad area experiences the trend of air temperature rise. A significant temperature rise is recorded during winter and spring period, while similar trend of rise is noticed when minimum average temperatures are observed. On the other hand, average maximum values show a rather slower trend of rise or even the fall in temperature, while a significant trend of air temperature fall is recorded during summer and spring periods.

SUMMARY -The aim of the study was to evaluate macular thickness and macular volume in unilateral and bilateral exfoliation syndrome and to compare them with exfoliative glaucoma and control eyes using optical coherence tomography. This prospective study included 114 subjects (228 eyes) divided into 4 groups according to the presence of exfoliation: 30 patients with unilateral syndrome, 24 patients with bilateral syndrome, 28 patients with bilateral glaucoma and control group without glaucoma or exfoliation syndrome (32 subjects). All subjects were older than 50 years. Patients with visual acuity under 0.6 according to Snellen were excluded, as well as those with refraction errors, i.e. hypermetropia over +3 spherical diopters, myopia over -5 spherical diopters, astigmatism over 2 cylindrical diopters, patients with affections that might affect the macula or the optic nerve, such as diabetic retinopathy, macular degeneration, macular edema, epiretinal membrane, vascular occlusions, neuropathies, and patients having undergone eye surgery except for pseudophakic patients with visual acuity within the set limits. Study results confirmed the hypothesis on the existence of structural changes of macular parameters before the functional ones, thus representing an early sign of glaucomatous damage in risk groups such as unilateral and bilateral exfoliation syndrome. If the glaucoma had already manifested (exfoliative glaucoma in this study) with changes in optic disc and visual field, structural changes confirmed the clinical findings and warned of the disease severity.

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Апстракт: Глобални тренд забрињавајућег раста задужености с краја прошлог и почетка овог стољећа покренуо је озбиљне расправе о доктринарним и управљачким аспектима овог феномена с циљем формулисања дјелотворних стратегија управљања дугом и генерисаном кризом финансијског и реалног сектора. Задуженост Босне и Херцеговине се примарно манифестује као задуженост ентитета, Републике Српске и Федерације јер се дугови алоцирају. Како ниво дуга у значајној мјери утиче на каматне стопе симптоматично је зашто је цијена капитала (камата) висока кад Босна и Херцеговина и ентитети не спадају у ред презадужених земаља. Надамо се да ће овај рад дати бар део одговора за неутрализацију адресираних узрочника рецесије и генерисаних посљедица!? С друге стране, проблеми које генерише рецесија су тешко рјешиви у постојећем институционалном сетингу (OHR, currency board) који евидентно нема капацитет да креативно управља промјенама, али, изгледа, не постоји ни интерес(!?) кључних политичких фактора да се у постојећем механизму мијења било шта, тако да несклад овлаштења и одговорности континуелно генерише не само политичке неспоразуме, него и негативне импликације на економски положај и интересе Босне и Херцеговине и Републике Српске!? Да би се такве околности промијениле потребна је политичка воља и консензус да се сопствени проблеми морају превасходно рјешавати сопственим снагама. Има ли у актуелном тренутку академске, политичке и друштвене сагласности да се крене тим путем!?