<p class="abstract">Laser speckle contrast imaging (LSCI) is a useful device which is recruited for visualizing full-field microcirculatory images. The speckle pattern is produced as a consistent light illuminates a rough object, and the backscattered radiation is transformed into images and be shown on a screen. Movement within the object results in the fluctuation of patterns over time. Similar information can be attained by employing the Doppler effect, which needs to be scanned again. However, LSCI renders similar data without any further scanning procedure. Nowadays, LSCI has gained expanded consideration, in part because of its accelerated adoption for blood flow studies in the different surgical departments. Here we represent and review the application of LSCI methods of visualizing the field of microcirculation as medical applications from different clinical aspects and discuss the drawbacks that hinder its approval clinically.</p>