Aim: Behçet's disease is a multi-systemic autoimmune disease, characterized with recurrent oral-genital ulcers and uveitis. Neuro-Behçet's disease (NBD) may rarely cause tumour like brain lesions. Methods:Here we present a case of forty-two-year-old Turkish male with tumour like brain lesion whose tissue biopsy result was compatible with necrotic inflammation, perivascular polymorphonuclear leukocytes (PMNL), lymphocytes and other inflammatory cells infiltration. Bacterial and fungal blood cultures were negative. The patient was diagnosed with NBD and was treated with intravenous methylprednisolone 1000 mg/day for 5 days. His neurologic examination improved significantly with the treatment. We evaluated histopathological properties of all biopsy proven cases reported so far in the literature including our case.Results: When tumour-like lesions were seen in patients who had Behçet's disease in past medical history, NBD should be considered for preventing unnecessary brain operation. Seventy-three percent of all biopsy proven tumefactive NBD cases had inflammatory cell infiltration in the tumour like lesion area. Conclusion:After excluding infectious aetiology, high dose IV methylprednisolone should be begun as soon as possible in spite of mass effect that is compatible with tumour in brain magnetic resonance imaging (MRI); the good response to steroid supports to the diagnosis of tumefactive NBD. Although most tumefactive NBD patients have inflammatory infiltration in biopsy material why some cases do not have any inflammatory cell infiltration in acute lesion area needs to be clarified in further research.

After the head, the hands and upper extremities are the most frequently injured body parts in the paediatric population. Such injuries are among the most common causes of paediatric admission to the emergency department. 1 Upper extremity fractures and contusions are the main reasons for paediatric hand injuries, but tendon injuries are not uncommon. 2 The ratio of flexor to extensor tendon injuries is higher in the paediatric population than in adults. For children under 10 years of age, flexor tendon injuries are more common than extensor tendon injuries. 3,4 Flexor tendon injuries are not always easily diagnosed in children due to poor communication between physicians and patients and the limited compliance of children in the motor function assessment. 5,6 Moreover, isolated flexor tendon injuries are infrequent: neurovascular injuries usually accompany tendon injuries, and especially digital nerve injuries may be masked by limited cooperation. 6 The small size of the involved structures may also pose a challenge to their repair and reconstruction; therefore, meticulous surgical skills are required for the paediatric population.There are also some differences

No abstract

Amaç: Serebrovasküler hastalıklar özellikle ileri yaştaki hastalarda epileptik nöbetlerin önemli nedenlerinden biridir. Bu çalışmanın amacı akut iskemik inmeli hastalarda görülen erken nöbetlerin insidansını, prediktif faktörlerini ve prognoz üzerine etkisini araştırmaktır.Gereç ve Yöntem: Bu çalışmada akut iskemik inmesi olan 619 hastanın dosyaları incelendi. Erken nöbetler, Uluslararası Epilepsi ile Savaş Derneği (ILAE) kriterlerine göre inmeden sonraki bir hafta içinde ortaya çıkan nöbetler olarak tanımlandı. Hastaların demografik özellikleri, risk faktörleri, başvuru sırasındaki National Institutes of Health Stroke Scale (NIHSS) skorları, serum C-reaktif protein (CRP) düzeyleri ve trombosit sayıları ile hastaların takiplerindeki modifiye Rankin Skalası (mRS) skorları ve diffüzyon ağırlıklı görüntülemede lezyon yerleşimi kaydedildi.Bulgular: Çalışmaya 22 (%3.6) erken nöbet geçiren (10 kadın [45.5%]; ortalama yaş, 66.55±15.3 yıl) ve 597 (%85.5) erken nöbet geçirmeyen (280 kadın [%46.9]; ortalama yaş, 69.5±13.3 yıl) hasta dahil edildi. Başvuru sırasındaki NIHSS skoru ortalaması, CRP düzeyleri ve trombosit sayıları, hastanede mortalite, izlemde mRS skoru ve rekürren inme oranları erken nöbet geçiren grupta anlamlı olarak daha yüksek idi (p<0.05). Lojistik regresyon analizinde başvuru sırasındaki NIHSS skoru, trombosit sayısı ve rekürren inme, erken nöbetler ile anlamlı olarak ilişkili bulundu (p<0.05). Sonuç:Artmış trombosit sayısı ve başvuru sırasındaki inme şiddeti akut iskemik inme hastalarında erken nöbetler için ana risk faktörleri olarak görünmektedir.Anahtar sözcükler: Erken nöbetler; iskemik inme; prediktif faktörleri.