The successful and safe development of economic activities that create conditions for compliance with the rational nature management principles involves maintaining a balance between the economic potential of society and the ecological potential of the environment. The natural resources are the basis for the development of production forces and rational environmental management. To ensure safety of natural ecosystems, it is necessary to pay attention to the characteristics of the the natural resource potential of the territory, which determines the production and economic orientation of the territory. The territorial distribution of production forces depends on the type of economic activity ensuring its stable economic development. Omsk region occupying a vast territory from south to north is characterized by a variety of natural and climatic features. A significant difference in heat and moisture supply predetermines a difference in the economic development of the r territory. The study of zonal distribution of energy resources and their temporal variability has always been crucial. The current study assesses thermal resources of Omsk region: values of the components of the heat energy balance are determined, patterns of their territorial distribution are revealed, and types of dependences are identified. The data obtained are of great importance in assessing the interaction of the environment and anthropogenic activities. Quantitative indicators of heat and power resources and moisture supply can be used in the long-term planning of economically effective economic activities and to increase the capacity of production forces of the agroindustrial complex.