Increasing the valuable component content in a pregnant solution due to the activation of leaching solution with cavitation treatment in case of the borehole in-situ leaching (ISL). Methods.To obtain the cavitation effect, a laboratory cavitation plant has been produced. Studies on the sulphuric acid solution activation by means of cavitation were conducted using solutions with 10 g/l of acid content. Studies of changing the sulphuric acid solution activity during treatment with a cavitator were conducted for 3 minutes (24 passes through the cavitator), 5 minutes (40 passes), 10 minutes (80 passes) and 20 minutes (160 passes). The content in the solution of the valuable component was analysed using a KFK-3-"ZOMS" photoelectric photometer.Findings. The laboratory studies have been performed to set the influence of the cavitation process on the leaching solution activity at various degrees of activation and time of reaction. The studies have established that in order to activate the leaching solution, it is proposed to carry out cavitation treatment of sulphuric acid before to additionally fortify the mother solution, which helps to increase its activity. The solution activation leads to an increase in the valuable component content from 18 to 26% in the pregnant solution and its activity is maintained for a long time (up to 30 days).Originality. New dependences have been obtained reflecting the nature of changing the valuable component content in the pregnant solution on the reaction time and the degree of solution activation. Practical implications.The proposed activation method leads to an increase in the valuable component content in the pregnant solution compared to the basic technology, therewith, the activity is maintained for a long time. The proposed technology is characterized by low capital costs, is easily integrated into the existing system and is absolutely environmentally friendly.