No abstract

No abstract

Objective The characteristics of bladder calculi and their correlation with hypertension in Southern Hunan, China were analyzed retrospectively to guide the prevention and treatment of bladder calculi and hypertension. Materials and methods A retrospective cohort study of medical records was conducted in the First Affiliated Hospital of University of South China from December 2017 to December 2021. The subjects were patients over 14 years old who were diagnosed with bladder calculi by imaging examination and whose calculi were removed. Analysis was conducted on the patients’ basic characteristics and calculus composition, characteristics, and relationship with hypertension. Results A total of 352 cases of bladder calculi were enrolled. The age ranged from 15 years to 89 years with an average of (65.56 ± 11.94) years. Most of the respondents came from rural areas (61.4%). Calcium oxalate was the main component of the stones. Calcium oxalate and carbonate apatite were the most common mixed stones, and pure uric acid was the most common single stone. The pure uric acid stones were significantly larger than the pure calcium oxalate stones (P < 0.05). In addition, 26.1% of the patients with bladder calculi experienced hypertension. Binary logistic regression showed that hypertension was an independent risk factor for bladder calculi (B = 2.584, OR = 1.685, P < 0.05). Conclusion The management of bladder calculi in Southern Hunan can be guided by local demographic data. Hypertension may be one of the independent risk factors for bladder calculi.

Background: Malignant obstructive jaundice (MOJ) has a low immediate surgery rate (10-20%) and a poor post-resection survival rate. Although several clinical results have demonstrated the safety and efficacy of stent placement combined with radioactive seeds, the existing implantation methods are time consuming and prone to error. In this study, we introduced a self-made delivery system and novel implantation method for a self-expandable metallic stent (SEMS) with 125 I seed strand and evaluated its feasibility and efficacy in MOJ patients.Methods: Our self-made delivery system was applied to 61 patients (39 males and 22 females, mean age 66.36±10.73 years) from October 2018 to June 2020 in our center with a novel implantation method. The preparation and manipulation processes were described in detail. Technical and clinical successes were recorded, and stent patency and overall survival (OS) were assessed. A P value of less than 0.05 indicated a significant difference.Results: Stents with 125 I seed strands were successfully placed in all 61 participants with our novel implantation method. The clinical success rate was 96.7%, and no severe procedure-related complications were found except bile leakage through puncture in 1 participant. The median duration of primary stent patency was 120 (37, 233.5) days, and the median OS was 169 (41, 270) days.Conclusions: Our self-made delivery system with a novel SEMS implantation method with 125 I seed strand was feasible and effective for MOJ patients and significantly simplified the current implantation approach.