No abstract

BackgroundTo determine the effects of noninvasive mechanical ventilation (NIV) compared with invasive mechanical ventilation (IMV) as the initial mechanical ventilation on clinical outcomes when used for treatment of acute respiratory failure (ARF) in immunocompromised patients.MethodsWe searched PubMed, EMBASE, the Cochrane Central Register of Controlled Trials (CENTRAL), the Chinese Biomedical Literature Database (CBM) and other databases. Subgroup analyses by disease severity and causes of immunodeficiency were also conducted.ResultsThirteen observational studies with a total of 2552 patients were included. Compared to IMV, NIV was shown to significantly reduce in-hospital mortality (OR 0.43, 95 % CI 0.23 to 0.80, P value = 0.007) and 30-day mortality (OR 0.34, 95 % CI 0.20 to 0.61, P value < 0.0001) in overall analysis. Subgroup analysis showed NIV had great advantage over IMV for less severe, AIDS, BMT and hematological malignancies patients in reducing mortality and duration of ICU stay.ConclusionsThe overall evidence we obtained shows NIV does more benefits or at least no harm to ARF patients with certain causes of immunodeficiency or who are less severe.Electronic supplementary materialThe online version of this article (doi:10.1186/s12890-016-0289-y) contains supplementary material, which is available to authorized users.

This article examines the life stories of women leaders in the People's Republic of China, particularly their paths to leadership, in the context of sociohistorical changes that have unfolded in China since the late 1970s. It illustrates how women developed their attitudes toward leadership roles and their unique leadership style. By unveiling the dynamic interplay between culture and institutional factors presented by social change, the authors argue that the choices these women leaders made were shaped by their continual efforts to reconcile conflicting roles arising from two axes: the "expertofficial" and the "private-public" dichotomies. The article concludes with an urgent call to policymakers to protect the rights of Chinese women by developing a workplace policy that promotes gender equality at the top of the political pyramid. Such a policy would take into consideration the inherent frictions and dilemmas experienced by Chinese women leaders.

No abstract