Cardiovascular diseases are critical human illnesses which are increasing year by year. 1 Coronary arteriosclerosis can interrupt cardiac blood circulation, resulting necrosis of myocardium after ischaemia and hypoxia. 2,3 H 2 O 2 is produced in ischaemia-reperfusion injury (I/R), contributing to ROS in oxidative stress injury. 4 Apoptosis of myocardial cells occurs in a variety of heart diseases, such as cardiomyopathy, myocardial ischaemia/reperfusion injury, myocardial infarction and congestive heart failure. 5,6,7 Thus, it is essential to suppress excessive apoptosis in myocardial cells in cardiovascular diseases.