The relevance of the scientific work is because the studied sector is one of the sources and consumers of innovative development, which, in turn, can increase the economic growth of the state and bring the economic policy of the Republic of Kazakhstan to a new level. Thus, the purpose of the study is to study all aspects of the topic under study, namely theoretical, thanks to which the main signs and principles of activity will be revealed, but also practical, which will be able to show the implementation of the fixed principles in the economic policy of the Republic of Kazakhstan. Various methodological approaches of theoretical and practical nature were used in the scientific work, namely the theoretical-methodological approach, the dialectical methodological approach, the method of analysis, the method of comparative analysis, the functional methodological approach, the method of synthesis, and the method of analysis of scientific literature. In the course of scientific research in the field of studying the economic mechanism of stimulating business entities in the manufacturing industry, the results were revealed, namely, consideration of the theoretical component of the work in defining the concept, signs, and principles of activity of the sector of the economic mechanism of stimulating business entities as a whole, as well as in the field of studying the manufacturing industry. The practical aspect of scientific work was studied, which was based on the study of the experience of the functioning of the sector on the territory of the Republic of Kazakhstan and foreign countries. The results obtained in the course of the scientific work will help to identify problems that hinder the proper functioning of such a sector, as well as to develop recommendations for improving the sector of the economic mechanism for stimulating business entities in the manufacturing industry. JEL Classification: B41, O14