No abstract

Objective: This Meta-analysis was aimed to systematically studying the effects of muscle strength training on the walking ability like balance ability, mobility ability of Parkinson's disease patients and then provide useful theoretical reference to further researches on exercise treatments on Parkinson's disease by retrieving and collecting articles about muscle strength training. Methods This literature review was finally determined on searching PubMed, Elsevier, Web of science, China Journal Full-text Database (CNKI), WanFang Data and other Chinese and foreign databases and combined with manual search. The limit of the search time was from the date when the literature was recorded to 2019. A comprehensive collection of randomly controlled trials of muscle strength training on the walking ability of Parkinson's patients was done. Researchers used the Cochrance risk assessment tool to evaluate the methodological quality of the selected articles, and the ReMan 5.3.5 software to statistically process the obtained data. Results A total of 13 RCTs and 627 samples were included in this study. Meta-analysis of BBS balance scale show that MD=4.67 (95%CI, I 2 =97%, P=0.52) between muscle strength training group and non-exercise intervention group; MD=-2.67 between muscle strength training group and exercise intervention control group (95%CI, I 2 =7%, P<0.00001); TUGT Meta-analysis show that MD=-1.06 (95%CI, I 2 =75%, P=0.10) between muscle strength training group and non-exercise intervention group; MD=0.09 (95%CI, I 2 =0%, P=0.31) between the muscle strength training group and the control group with exercise intervention; 10MWT Meta-analysis show MD=-0.28 (95%CI), I 2 =98%, P<0.29) between the muscle strength training group and the control group with exercise intervention; Stride length Meta-analysis show MD=-1.85 (95%CI, I 2 =68%, P=0.63) between the muscle strength training group and the control group without exercise intervention; MD=-1.75 (95%CI, I 2 =32%, P=0.56) between the muscle strength training group and the control group with exercise intervention; MD=-1.75 (95%CI, I 2 =32%, P=0.56). Meta-analysis of stride speed show MD=-0.02 (95%CI, I 2 =0%, P=0.46) between muscle strength training group and control group without exercise intervention; MD=-0.03 (95%CI, I 2 =35%, P=0.52) between the muscle strength training group and control group with exercise intervention. Conclusion Muscle strength training can significantly improve the balance ability, mobility, and walking ability of Parkinson's disease patients, but it has no significant benefits on improving stride length and walking speed.