BTO/MoS2@CA , with the integration of charge‐enhanced enzymatic activity, pH‐responsive CA release‐mediated H2O2 self‐supply, and GSH depletion, enables out‐of‐balance redox homeostasis, leading to effective tumor ferroptosis. As demonstrated by Yawei Lv, Xin Yu, Jing Liu, Chunying Chen et al. in their Research Article (e202217448), charge is one of the important contributing factors for nanozyme activity, which has not been mentioned previously.

Articles you may be interested in Comparison of crystal growth and thermoelectric properties of n-type Bi-Se-Te and p-type Bi-Sb-Te nanocrystalline thin films: Effects of homogeneous irradiation with an electron beam Electron-irradiation-induced divacancy in lightly doped silicon The recovery of the electrical resistivity and thermoelectric power in a number of n-and p-type a-tin samples, irradiated at low temperature, is considered. Three distinct first-order stages in the temperature range 20-50 K are observed. A fractional defect recovery has been deduced such that relative percentages of lA : 18 : Ie =90 : 4 : 6 anneal in the three stages. Activation energy scaling factors were found to be 69, 94, and 122 meV, respectively, for the three stages. Carrier mobilities as functions of carrier and defect concentration were calculated and found to be in good agreement with previously published values. Estimates for these quantities were also deduced when the samples were near to their intrinsic states (n. ~ nh)' A c1ose-pair-defect charge carrier trapping model provides a consistent explanation for all damage and recovery data.

AIMTo assess the prognostic value of lymphovascular invasion (LVI) in Bismuth-Corlette type IV hilar cholangiocarcinoma (HC) patients.METHODSA retrospective analysis was performed on 142 consecutively recruited type IV HC patients undergoing radical resection with at least 5 years of follow-up. Survival analysis was performed by the Kaplan-Meier method, and the association between the clinicopathologic variables and survival was evaluated by log-rank test. Multivariate analysis was adopted to identify the independent prognostic factors for overall survival (OS) and disease-free survival (DFS). Multiple logistic regression analysis was performed to determine the association between LVI and potential variables.RESULTSLVI was confirmed histopathologically in 29 (20.4%) patients. Multivariate analysis showed that positive resection margin (HR = 6.255, 95%CI: 3.485-11.229, P < 0.001), N1 stage (HR = 2.902, 95%CI: 1.132-7.439, P = 0.027), tumor size > 30 mm (HR = 1.942, 95%CI: 1.176-3.209, P = 0.010) and LVI positivity (HR = 2.799, 95%CI: 1.588-4.935, P < 0.001) were adverse prognostic factors for DFS. The independent risk factors for OS were positive resection margin (HR = 6.776, 95%CI: 3.988-11.479, P < 0.001), N1 stage (HR = 2.827, 95%CI: 1.243-6.429, P = 0.013), tumor size > 30 mm (HR = 1.739, 95%CI: 1.101-2.745, P = 0.018) and LVI positivity (HR = 2.908, 95%CI: 1.712-4.938, P < 0.001). LVI was associated with N1 stage and tumor size > 30 mm. Multiple logistic regression analysis indicated that N1 stage (HR = 3.312, 95%CI: 1.338-8.198, P = 0.026) and tumor size > 30 mm (HR = 3.258, 95%CI: 1.288-8.236, P = 0.013) were associated with LVI.CONCLUSIONLVI is associated with N1 stage and tumor size > 30 mm and adversely influences DFS and OS in type IV HC patients.