<b><i>Background:</i></b> Allergic rhinitis is an allergic inflammation of the nasal airways, and chronic rhinosinusitis is an inflammation of the paranasal sinuses. It can be induced by infection, allergy, or autoimmune problems. Diagnosis of these two diseases is made primarily based on clinical symptoms, allergen test, and imaging. The allergen test is invasive and expensive. The imaging test is harmful to children. Measurement of nasal nitric oxide (NNO) was noninvasive, without radiation, and inexpensive. This study was to evaluate the clinical significance of NNO in preschool children with nasal inflammatory diseases. <b><i>Methods:</i></b> A total of 55 cases of allergic rhinitis, including 35 mild cases and 20 moderate to severe cases, and 33 cases of chronic rhinosinusitis, including 18 mild cases and 15 moderate to severe cases were selected as the experimental group. Fifty healthy preschool children were chosen as the control group. The levels of NNO in all children were measured. The differences in the levels of NNO among allergic rhinitis, chronic rhinosinusitis, and the control group were compared. The levels of NNO in the control group were also analyzed. <b><i>Results:</i></b> The levels of NNO were significantly higher in preschool children with allergic rhinitis than in the control group, and the differences were significant. However, the levels of NNO in preschool children with chronic rhinosinusitis were lower than in the control group. In the control group, the levels of NNO were not significantly different between genders, and no significant correlation between NNO levels and the children’s height was found. <b><i>Conclusion:</i></b> As a noninvasive method for detecting nasal inflammatory diseases, measuring the levels of NNO had a high clinical significance in preschool children.
In order to improve the synergy level of marine disaster monitoring and early warning in coastal cities, an evaluation index system of 21 factors with 5 dimensions was constructed based on the synergy theory. The weights of all levels of indicators were determined by coefficient of variation method, and 24 representative coastal cities in China were evaluated by multi-level grey relational method. The evaluation results show that: the level of synergy in each dimension of 24 coastal cities is uneven, and the distribution level is not high. The level of synergy of marine disaster monitoring and early warning in coastal cities is positively correlated with the level of economic development. The level of synergy of monitoring and early warning of marine disasters in 24 coastal cities is not high, which is generally distributed in medium and low levels. Furthermore, according to the evaluation results and the current situation of marine disaster monitoring and early warning in coastal cities, a network organization structure is proposed to enhance the synergy ability of coastal city monitoring and early warning, so as to provide practical basis for the construction of China's coastal cities in the global marine disaster monitoring and early warning synergy.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.