Background: Whether the patients with coronavirus disease 19 (COVID-19) infected by severe acute respiratory syndrome (SARS)-CoV-2 would commonly develop acute kidney injury (AKI) is an important issue worthy of clinical attention. This study aimed to explore the effects of SARS-CoV-2 infection on renal function through analyzing the clinical data of 116 hospitalized COVID-19-confirmed patients. Methods: One hundred sixteen COVID-19-confirmed patients enrolled in this study were hospitalized in the Department of Infectious Diseases, Renmin Hospital of Wuhan University from January 14 to February 13, 2020. The recorded information includes demographic data, medical history, contact history, potential comorbidities, symptoms, signs, laboratory test results, chest computer tomography scans, and treatment measures. SARS-CoV-2 RNA in 53 urine sediments of enrolled patients was detected by real-time reverse transcription-polymerase chain reaction. Results: Twelve (10.8%) patients showed mild increase of blood urea nitrogen or creatinine (<26 μmol/L within 48 h), and 8 (7.2%) patients showed trace or 1+ albuminuria in 111 COVID-19-confirmed patients without chronic kidney disease (CKD). All these patients did not meet the diagnostic criteria of AKI. In addition, 5 patients with CKD who were undergone regular continuous renal replacement therapy (CRRT) before admission were confirmed infection of SARS-CoV-2 and diagnosed as COVID-19. In addition to therapy for COVID-19, CRRT was also applied 3 times weekly during hospitalization for these 5 patients with CKD. In the course of treatment, the renal function indicators showed stable state in all 5 patients with CKD, without exacerbation of CKD, and pulmonary inflammation was gradually absorbed. All 5 patients with CKD were survived. Moreover, SARS-CoV-2 RNA in urine sediments was positive only in 3 patients from 48 cases without CKD, and 1 patient had a positive for SARS-CoV-2 open reading frame 1ab from 5 cases with CKD. Conclusion: AKI was uncommon in COVID-19. SARS-CoV-2 infection does not result in AKI, or aggravate CKD in the COVID-19 patients.

In the past decades, research efforts on polyanion-type cathode materials by the scientific community intensified significantly. This paper reviews the latest advances in the exploration and development of polyanion-type compounds as high performance cathode materials for Li-ion batteries. It focuses on the synthesis, structure and physicochemical (especially electrochemical) properties of several classes of polyanion compounds. The relationship between composition-structure-performance of the novel electrode materials is also summarized and analyzed. The main approaches, achievements and challenges in this field are briefly commented and discussed.National Natural Science Foundation of China[20873115, 21021002, 90606015]; National Basic Research Program of China (973 program)[2007CB209702, 2011CB935903

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Garnet-type solid-state electrolytes (SSEs) are considered to be a good choice for solid-state batteries, yet the interfacial issues with metallic Li limit their applications. Herein, we propose an ultrasimple and effective strategy to enhance the interfacial connection between garnet SSEs and Li metal just by drawing a graphite-based soft interface with a pencil. Both experimental analysis and theoretical calculations confirm that the reaction between the graphite-based interfacial layer and metallic lithium forms a lithiated connection interface with good lithium-ionic and electronic conductivity. Compared to the reported interfacial materials, the graphite provides a soft interface with better ductility and compressibility. With improvement by this soft interface, the impedance of symmetric Li cells significantly decreases and the cell cycle is stable for over 1000 h. Moreover, a solid-state battery with Li-metal anode, ternary NCM523 cathode, and treated-garnet SSEs is fabricated and displays excellent rate capability and long cycling performance.

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