3-Selenyl/sulfenyl chromones/thiochromones were conveniently synthesized from the PIFA-mediated reactions between alkynyl aryl ketones bearing an ortho-methoxy/methylthio group and diorganyl diselenides/disulfides. This metal-free approach is postulated to first undergo the formation...

DMSO/SOCl2 was found to be an effective system for the intramolecular cyclization of 2‐alkynylbenzoates or 2‐alkynylbenzoic acids, which can afford biologically interesting 4‐(methylthio)isochromenones through regioselective electrophilic 6‐endo‐dig cyclization. DMSO plays the roles of both solvent and sulfur source and can also be replaced with its deuterated counterpart [D6]DMSO, enabling the incorporation of the SCD3 moiety into the isochromenone skeleton.

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