No abstract

Non-suicidal self-injury (NSSI) is a worrying phenomenon that is prevalent among young people. Prior theorizing and empirical evidence suggest that parenting may play a role in the etiology of NSSI. Thus, we conducted a systematic review to examine the association between parenting behaviors and parenting styles with NSSI in young people. Methods: The following databases were searched for relevant articles in July 2020: PubMed, EMBASE, CINAHL Plus, and PsycINFO. Studies were included if they sampled young persons aged 10–25 years old with a history of NSSI, assessed parenting behavior or style, and tested associations between parenting and NSSI outcomes. Results: A total of 26 studies were included in this review. Among parenting behaviors, low parental support, high psychological control, and high reactive control were more consistently associated with NSSI. Conversely, the evidence for behavioral control is equivocal. There is some evidence that invalidating parenting is also associated with NSSI. Conclusion: Consistent with the wider adolescent psychopathology literature, parenting that is perceived to be supportive, less psychologically controlling and reactive/punitive were less likely to be associated with NSSI. However, these results were largely based on child reports of parenting. Limitations and directions for future research are discussed.

Current evidence suggests that dating app users experience greater body dissatisfaction than nonusers. However, these were mostly based on studies of sexual minority men (SMM) or studies that did not consider the effects of sexual orientation. In this study, we reexamined the association between dating app use and male body image using two culturally diverse samples, taking into account the potential confounding or moderating effect of sexual orientation. Male participants from Singapore (n = 201; 71 users) and Sweden (n = 279; 108 users) completed an online survey on dating app use and measures of body image disturbance and dissatisfaction. Hierarchical regression analyses revealed that while dating app use indeed predicted overall dissatisfaction and muscularity dissatisfaction in the Singaporean sample, and body image disturbance, overall dissatisfaction, and height dissatisfaction in the Swedish sample, this ceased to be the case after we controlled for sexual orientation, except for height dissatisfaction in the Swedish sample. A moderation effect was also found in the Swedish sample: while SMM users had greater muscularity dissatisfaction than nonusers, this difference was not seen for heterosexual men. This study highlights the importance of considering both sexual orientation and cultural differences in the relationship between dating app use and body image. Public Significance StatementDating app use is purported to be associated with poorer body image. However, we found that after accounting for sexual orientation, dating app use largely ceased to predict male body image outcomes. Thus, dating app use may not be as problematic as previously thought, and if any, its effects appear to be particular to sexual minority men.

No abstract

Objective Frontotemporal dementia (FTD) encompasses a spectrum of neurodegenerative disorders, including behavioural variant FTD (bvFTD), semantic variant primary progressive aphasia (svPPA) and non‐fluent variant PPA (nfvPPA). While a strong genetic component is implicated in FTD, genetic FTD in Asia is less frequently reported. We aimed to investigate the frequency of Southeast Asian FTD patients harbouring known genetic FTD variants. Methods A total of 60 FTD‐spectrum patients (25 familial and 35 sporadic) from Singapore and the Philippines were included. All underwent next‐generation sequencing and repeat‐primed PCR for C9orf72 expansion testing. Neurofilament light chain (NfL) levels were measured in a subset of patients. Results Overall, 26.6% (16/60 cases) carried pathogenic or likely pathogenic variants in a FTD‐related gene, including: MAPT Gln351Arg (n = 1); GRN Cys92Ter (n = 1), Ser301Ter (n = 2), c.462 + 1G > C (n = 1); C9orf72 expansion (35–70 repeats; n = 8); TREM2 Arg47Cys (n = 1); and OPTN frameshift insertion (n = 2). Genetic mutations accounted for 48% (12/25) of patients with familial FTD, and 11.4% (4/35) of patients with sporadic FTD. C9orf72 repeat expansions were the most common genetic mutation (13.3%, 8/60), followed by GRN (6.7%, 4/60) variants. Within mutation carriers, plasma NfL was highest in a C9orf72 expansion carrier, and CSF NfL was highest in a GRN splice variant carrier. Interpretation In our cohort, genetic mutations are present in one‐quarter of FTD‐spectrum cases, and up to half of those with family history. Our findings highlight the importance of wider implementation of genetic testing in FTD patients from Southeast Asia.