The patient was a 62-year-old man diagnosed as having prostatic extra-gastrointestinal stromal tumor (EGIST) who was treated with imatinib. No recurrence or metastasis was found after a 6-month follow-up. We identified 14 cases of prostatic primary EGIST in PubMed and summarized these cases with our case. The patients’ ages ranged from 31 to 78 years (average: 53.6 years), and most patients’ prostate-specific antigen (PSA) concentrations were within normal limits (92.9%, 13/14). All patients underwent imaging examinations; prostatic masses measured 6 to 14.2 cm (mean: 9.43 cm), and imaging excluded secondary prostatic masses from the intestinal tract. By immunohistochemical staining, the tumors were positive for cluster of differentiation (CD)117 (71.4%, 10/14), DOG1 (100%, 7/7), and CD34 (100%, 14/14), and negative for smooth muscle actin (SMA) (71.4%, 10/14), desmin (100%, 11/11), and S100 (100%, 12/12). Treatment depended on the results of the gene mutation detection as well as the risk estimation according to tumor size and microscopic mitotic rates (>5 per 50 high-power fields: 60%, 6/10). Among the 12 patients with reported outcomes, nine achieved good results (no recurrence or metastasis), one achieved reduced mass volume, one experienced recurrence, and one died.

N-methyl pyrrolidonium hydrosulfate ([Hnmp]HSO4) was synthesized and characterized. N-butyl acetate was synthesized from acetic acid and n-butanol with [Hnmp]HSO4 as catalyst in a catalytic rectification column 30 mm in diameter and 2.5 m in height. Effects of catalyst dosage, bottom temperature, feeding ratio of acetic acid to n-butanol, feeding method and reflux ratio on esterification and rectification were investigated. Under optimal condition which taking both energy cost and product quality into account: catalyst dosage was 0.5% of feed weight, bottom temperature was 120 °C, mole ratio of acetic acid to butanol was 1:1.2, acetic acid and butanol were mixed and fed above second section of packing, feeding rate was 150 mL/h and reflux ratio was 4, mass fraction of n-butyl acetate in bottom could reach 92.49 %.

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