A highly effective visible light-promoted "radical-type" coupling of N-heteroarenes with aryldiazonium salts in water has been developed. The reaction proceeds at room temperature with [Ru(bpy)3 ]Cl2 ⋅6 H2 O as a photosensitizer and a commercial household light bulb as a light source. Pyridine and a variety of substituted pyridines are effective substrates under these reaction conditions, and only monosubstituted products are formed with different regioselectivities. Using aqueous formic acid as solvent, an array of xanthenes, thiazole, pyrazine, and pyridazine are compatible with this new arylation approach. The broad substrate scope, mild reaction conditions, and use of water as reaction solvent make this procedure a practical and environmentally friendly method for the synthesis of compounds containing aryl-heteroaryl motifs.

An increase in the incidence of water-borne human diseases, such as diarrhea and emesis, has occurred due to drinking polluted water. These water-borne diseases can lead to death, if correct treatment is not provided. Assuring that drinking water quality is safe has been a crucial challenge for public health. Water contamination with pathogenic microorganisms represents a seriously increased threat to human health. Currently, different microorganisms are being used as the primary indicator to assess water quality total coliform and Escherichia coli (E. coli) being the most common. However, increasing the occurrence of water-borne illness from sources deemed safe by the microbial standard criteria has raised the question—are these microbial indicators reliable and sensitive enough to ensure water quality? Currently, other microorganisms including bacteria, enteric virus, and protozoa are being tested and used in different countries as alternative indicators to monitor water quality. It is necessary to study the diverse water quality indicator systems used throughout the world and their efficacy with the present water quality. Although water quality standards suggest adding pathogenic microorganisms such as enteric virus as an indicator, China only uses pathogenic E. coli, protozoa. Pin-pointing the shortage of the current water quality indicator system in China is crucial in order to propose changes in future water quality indicator systems.

Purpose: The objective of this study was to examine the influence of sexual identity and adverse childhood experiences (ACEs) on non-suicidal self-injury (NSSI) among rural high school students in less developed areas of China. Methods: Behavior risk factors data collected from 1810 students from a high school in Jiangxi province, China. Five measures of childhood abuse and household dysfunction were summarized, and ACE was divided into 0, 1, 2, 3–5 ACEs. Logistic regression analysis was used to explore the influence of sexual identity, adverse childhood experiences, and their interaction with non-suicidal self-injury. Results: Compared with heterosexual students, high school students who identify as lesbian, gay, or bisexual (LGB) have a higher tendency of non-suicidal self-injury (AOR = 3.250, 95% CI = 1.69–6.28, p < 0.01). There was also a graded relationship between cumulative ACEs exposure and non-suicidal self-injury behaviors (AOR = 1.627, 95% CI = 1.02–2.60, p < 0.05). Odds for NSSI are higher among students with both experienced ACEs and identified as LGB (AOR = 2.821, 95% CI = 1.51–5.29, p < 0.05). Conclusions: Non-suicidal self-injury is associated with ACEs exposure and with those who identify as LGB, and the NSSI odds are greater when students identify as LGB and have experienced ACEs. More interventions to reduce non-suicidal self-injury should focus on LGB and ACEs and more attention needs to be paid to those who identify as LGB and have been exposed to ACEs.

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A cloud point extraction (CPE) method was used as a pre-concentration strategy prior to the determination of trace levels of silver in water by flame atomic absorption spectrometry (FAAS) The pre-concentration is based on the clouding phenomena of non-ionic surfactant, triton X-114, with Ag (I)/diethyldithiocarbamate (DDTC) complexes in which the latter is soluble in a micellar phase composed by the former. When the temperature increases above its cloud point, the Ag (I)/DDTC complexes are extracted into the surfactant-rich phase. The factors affecting the extraction efficiency including pH of the aqueous solution, concentration of the DDTC, amount of the surfactant, incubation temperature and time were investigated and optimized. Under the optimal experimental conditions, no interference was observed for the determination of 100 ng·mL Ag in the presence of various cations below their maximum concentrations allowed in this method, for instance, 50 μg·mL for both Zn and Cu, 80 μg·mL for Pb, 1000 μg·mL for Mn, and 100 μg·mL for both Cd and Ni. The calibration curve was linear in the range of 1-500 ng·mL with a limit of detection (LOD) at 0.3 ng·mL. The developed method was successfully applied for the determination of trace levels of silver in water samples such as river water and tap water.