The Pisha sandstone-coverd area is among the regions that suffer from the most severe water loss and soil erosion in China and is the main source of coarse sand for the Yellow River. This study demonstrated a new erosion control method using W-OH solution, a type of hydrophilic polyurethane, to prevent the Pisha sandstone from water erosion. We evaluated the comprehensive effects of W-OH on water erosion resistance and vegetation-growth promotion through simulated scouring tests and field demonstrations on the Ordos Plateau of China. The results of simulated scouring tests show that the water erosion resistance of W-OH treated area was excellent and the cumulative sediment yield reduction reached more than 99%. In the field demonstrations, the vegetation coverage reached approximately 95% in the consolidation-green area, and there was almost no shallow trenches on the entire slope in the treated area. In comparison, the control area experienced severe erosion with deep erosion gullies appeared on the slope and the vegetation coverage was less than 30%. This study illustrated that W-OH treatment can protect the Pisha sandstone from erosion and provide the vegetation seeds a chance to grow. Once the vegetation matured, the effects of consolidation-growth mutual promotion can efficiently and effectively improve the water erosion resistance and ecological restoration.