Objective Pericardial adipose tissue volume (PATV) is related to the mechanism of coronary artery disease (CAD), but its association with CAD risk factors is not clear. This study aimed to investigate the relationships between PATV and its associated factors. Methods A total of 682 inpatients were consecutively enrolled in this study. Patients were divided into the high PATV group (PATV ≥174.5 cm3; n = 506) and low PATV group (PATV  < 174.5 cm3; n = 176). Multiple linear regression analysis was conducted to evaluate the related factors of PATV. Multivariable logistic regression was used to analyze the risk factors of CAD. Results Left ventricular fat volume, right ventricular fat volume, body mass index, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol were significant and independent risk factors of enlargement of PATV. Increased PATV was identified as an independent risk factor of CAD, and increased pulse pressure was also independently and positively correlated with CAD. Conclusions PATV is significantly correlated with the classic risk factors of CAD. Pulse pressure is also correlated with PATV. PATV is an independent risk factor of CAD, and pericardial adipose tissue may alternatively be used in non-invasive diagnostic examination of CAD.

To investigate the effects on its virulent phage lysis of Escherichia coli resistant mutation. Methods First, isolate the chloramphenicol-sensitive strains and resistant strains from the excrement samples. Then, isolate the virulent phage lysis using the sensitive strains as the host bacteria and extracted the resistant plasmids of the resistant strains to the chloramphenicol resistant transformation experiment to obtain mutant strains. Finally, examine the sensitivity of the sensitive strains, resistant strains and mutant strains. Result The sensitive strains and the mutant strains are sensitive to the phage and has lysis effects while the resistant strains are insensitive and have no lysis. Conclusion The lysis of E. coli phage has no direct relationships with the resistant character and has strain specificity. The mutant strains( sensitive strains with chloramphenicol resistance) still have sensitivity.