A new oleanolic-type triterpene glycoside, (3β,21β)-21-[(β-d-glucopyranosyl-(1→2)-β-d-glucopyranosyl)oxy]-3-hydroxyolean-12-en-28-oic acid (1), together with five analogues, oleanazuroside 1 (2), oleanazuroside 2 (3), 24-hydroxytormentic acid ester glucoside (4), 24-epi-pinfaensin (5), and oleanolic acid 3-O-α-l-arabinoside (6) were isolated from the n-butyl alcohol extract of Anchusa italica. Their structures were determined spectroscopically and compared with previously reported spectral data. Compounds 3-4 and 6 were evaluated for their cytotoxic activities against five human cancer cell lines, but only compound 6 showed moderate cytotoxicity.

Three new bisabolane sesquiterpenes, songaricalarins F–H (1–3, resp.), and five known analogs, 4–8, were isolated from roots and rhizomes of Ligularia songarica. The structures were elucidated by spectroscopic methods, including 2D‐NMR techniques. The isolated compounds were also evaluated for their cytotoxic activities, against human lung carcinoma (A‐549) and human breast adenocarcinoma (MCF‐7) cell lines, and three compounds were found to show moderate cytotoxicities.

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Three New Bisabolane Sesquiterpenes from Ligularia songarica. -Three new bisabolane sesquiterpenes, songaricalarins F-H, are isolated along with five know analogues. Three of these sesquiterpenes including songaricalarin F (I) show moderate cytotoxic activities. -(DAI, W.; XIE, Z.-J.; LI, M.; WANG*, Q.; Helv. Chim. Acta 98 (2015) 3, 410-416, http://dx.