Objective to investigate the effect of comprehensive nursing intervention on thyroid stimulating hormone (TSH) suppression for patients with differentiated thyroid cancer (DTC) in the Department of Nuclear Medicine. Methods From January 2016 to December 2016, a total of 90 patients with DTC, receiving 131 I treatment in the Department of Nuclear Medicine of the First Affiliated Hospital of Jinan University are enrolled in this study. All patients have received TSH suppression treatment for at least 3 months prior to admission, and are given individual-based comprehensive nursing intervention on TSH suppression after admission. Through questionnaire and telephone follow-up, patients' awareness of TSH suppression and their medication compliance before and after nursing intervention are analyzed and compared. Results The awareness of the knowledge of TSH suppression and medication compliance are significantly improved in 90 patients after comprehensive nursing intervention (P<0.05). Conclusions Individual-based comprehensive nursing intervention can effectively improve awareness of the knowledge of TSH suppression, medication compliance and confidence in cure in patients with DTC, which helps promote the harmonious relationship between nurses and patients and improve the prognosis of patients. The comprehensive nursing intervention is worthy of clinical application.

Purpose: To explore the effect of continuous quality improvement (CQI) of radiation safety management for patients administerediodine-131 after thyroid cancer surgery. Methods: A total of 103 patients with differentiated thyroid carcinoma were randomly divided into control and experimental groups containing 51 and 52 patients, respectively. In the control group, the drug was administered according to the operating procedure for iodine-131 treatment of thyroid carcinoma. In the experimental group, CQI was adopted to manage the radiation safety of care in addition to the conventional iodine-131 thyroid cancer treatment procedures. We also improved radiation safety protection measures prior to drug administration, developed a flow chart of drug administration for patients, established a patient preview of the drug administration process, and enhanced health education and psychological intervention for the patient. Results: The environmental radiation around the drug delivery window was reduced (P< 0.05), total duration of exposure to the radiation was shortened (P< 0.05), drug drop rate was decreased to 0%, and patient satisfaction was improved in the experimental group compared to the control group. Conclusions: Application of CQI for management of radiation safety when treating thyroid cancer withiodine-131 can improve patient treatment, quality of care, and satisfaction and reduce radiation pollution in the surrounding environment and radiation injury to staff.