Because of its versatile coordination modes and strong coordination ability, the mercaptoacetic acid substituted 1,2,4-triazole 2-{[5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid (H 2 L) was synthesized and characterized. Treatment of H 2 L with cobalt and nickel acetate afforded the dinuclear complexes {-, respectively. Complex 1 crystallized in the monoclinic space group P2 1 /c, while 2 crystallized in the tetragonal space group I4 1 /a. Single-crystal X-ray diffraction studies revealed that H 2 L is doubly deprotonated and acts as a tetradentate bridging ligand in complexes 1 and 2. For both of the obtained complexes, extensive hydrogen-bond interactions contribute to the formation of their threedimensional supermolecular structures. Hirshfeld surface analysis was used to illustrate the intermolecular interactions. Additionally, the urease inhibitory activities of 1, 2 and H 2 L were investigated against jack bean urease, where the two complexes revealed strong urease inhibition activities.