The feasibility of tracheal allotransplantation with a fascial vascular carrier was examined in three groups with varied dose sequences of immunosuppression. A control group (group 1) received no medication. The three experimental groups were given daily cyclosporine intramuscular doses of 5 mg/kg (group 2), 5 mg/kg plus 3 mg/kg methylprednisolone (Solu-Medrol) (group 3), and 10 mg/kg (group 4) for 6 weeks or until death. Grafts were assessed by silicone dye infusion of the artery of the fascial flap to examine their microcirculation and by quantitative histologic study. Group 1 evidenced complete rejection after a heterotopic revascularization period of 14 days. The allografts of the experimental groups remained viable after 14 days of revascularization and could be transplanted orthotopically after this period. After transplantation, the viability of group 2 tracheas was unpredictable with changes ranging from mild to complete rejection. Group 3 evidenced well-preserved transplant viability with infection-induced necrosis at the anastomoses caused by the corticosteroid component. All group 4 animals survived the follow-up period with normal allograft viability. Cyclosporine in a dosage of 10 mg/kg per day can effectively suppress the immune response after transplantation of vascularized tracheal allografts. This experimental model will allow future studies to examine airway wall immunogenicity.

This paper has researched traditional algorithms. The defects had been pointed out and proved. According to this, setup calculation algorithm was optimized. Considering strip transverse flow and creep deformation, natural output profile was defined. Practical applications in domestic 1500 hot strip mill show that the setup calculation strategy achieved good effect and enhanced the profile and flatness precision

The finite difference method model of temperature field and thermal crown of work roll on hot strip mill was researched. The temperature field and thermal crown were calculated, surface temperature distribution and thermal deformation were both reduced from center to edge. The computed and measured roll surface temperature were comparatively in good agreement with each other, practical application results show that the model has high calculating speed, high precision and can meet the needs of the strip shape on-line process control.

This paper has researched strip width model in hot strip rolling. Analyzed physical phenomena influencing strip width, established calculation model in production including width spread during flat rolling, width change induced by bending, width changed by high temperature creep and thermal expansion and contraction during rolling. Practical applications in domestic 1500 hot strip mill show that the width model achieved good effect and enhanced the calculation precision.

This paper, aimed at Ganglu 1500 hot strip rolling project, developed advanced shape control system. Entry profile calculation strategy was developed. Natural output profile was defined. Profile distribution model based on the buckling limit was developed. Practical applications in domestic 1500 hot strip mill show that the setup calculation strategy achieved good effect and enhanced the profile and flatness precision