Soil desertification affects the service functions of the ecosystem. In severe cases, it even causes a decline in agricultural productivity and shrinkage of animal husbandry, posing a threat to regional eco-environment and economic sustainability. The previous research on soil remediation research mainly concentrates on heavy metal degradation, saline soil improvement, and eroded and degraded soil improvement. There is little report on the biomass improvement and restoration of sandy soil. Therefore, this paper explores the remediation effect of biomass amendment on the physical-chemical performance and sustainable utilization of sandy soil in Huangyangtan, the largest sandy land in northern China’s Hebei Province. Specifically, the authors detailed the strategies to measure the physical-chemical indices and microbial diversity of Huangyangtan sandy soil, and introduced the materials and mode of the biomass amendment test on Huangyangtan sandy soil, followed by an elaboration on the test results. The influence of different test fertilizers on the soil was analyzed in four dimensions, namely, physical performance, chemical performance, biological performance, and crop yield. The results show that biomass amendment can effectively remediate sandy soil, and promote its sustainable utilization.