Mucosal lesions related to the wearing of a poorly adapted are frequent. Chronic irritations with sharp or excessive edge lead to hyperplasique reaction. Epulisfissuratum represents 15% of benign tumor of the jaws, is a pseudotumor growth located over the soft tissues of the vestibular sulcus caused by poorly adapted dentures. Treatment indication for these lesions is surgical excision with appropriate prosthetic reconstruction.This article exposes through a clinical case, the interest of a temporary denture followed by a surgical treatment, in healing the massive growth of vestibular oral mucosa in the mandible and maxilla associated with ill-fitting dentures. Prosthetic rehabilitation and function were achieved with the fabrication of new maxillary and mandibular complete dentures.