Objectives: Cervical cancer can be prevented by identifying the lifestyle and diet. The purpose of this research was to compare lifestyle and nutritional risk in Iranian women with cervical cancer and healthy women who referred to hospitals affiliated to Shahid Beheshti University of Medical Sciences, Tehran, Iran during 2015-2016. Materials and Methods: This descriptive-comparative study was conducted on 120 women referring to hospitals of Shahid Beheshti University of Medical Sciences, Tehran, Iran during 2015-2016. The data collection tool was a questionnaire that covered data on health-promoting lifestyle profile (HPLP), diet, and demographic characteristics. Finally, data were analyzed by SPSS software, using an independent t test, as well as chi-square and Mann-Whitney tests. Results: Statistical differences were observed between the number of delivery, smoking, and the smoking of the spouse although the difference in HPLP between the 2 groups was insignificant. However, healthy women could better manage their stress and interpersonal relations compared to women who had cervical cancer. As regards diet, fat was statistically different between the two groups (P<0.05). Conclusions: In general, a change in lifestyle, diet, reduced smoking can decrease the incidence of cervical cancer in women.