Olfactory dysfunction is a major challenge in medicine and there is no absolute treatment for anosmic patients. Adipose-derived mesenchymal stem cells (ASCs) are multipotent cells capable of differentiating into several cell lineages. The aim of present study was to assess effects of ASCs upon restoration of the olfactory function in anosmic rats.

A brief review of the salient literature is presented in regard to extramedullary plasmacytoma. The relevant clinical features, pathology, a n d methods of treatment are discussed. The eight cases seen by the authors are reviewed and their followup progress noted. The authors discuss a few interesting facets of extramedullary plasmacytoma.

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