A 24-year-old male with red tattoos developed ocular pain and blurred vision three years after having been tattooed. The patient also noticed redness and itching in the area of the tattooed skin (Fig. 1). The rest of the history and physical examination was unremarkable. Routine laboratory screening tests were within normal limits, with the exception of a mildly elevated white blood cell count (11,6 G/L). Chest X-ray examination and CT scan were within normal limits. Ophthalmological examination revealed panuveitis of the right eye with keratic precipitates, several firm posterior synechiae, infiltrated vitreous, and acute iridocyclitis of the left eye with ciliary congestion, flare and cells in the anterior chamber, and keratic precipitates (Figs. 2, 3). Histological examination of the lesion confirmed granulomatous reaction in the tattooed skin. Excision of the inflamed tattoo, administration of topical and systemic steroid (40 mg/day of prednisolone orally and 0,5% prednisolone acetate eye drops (2 drops twice daily) and cyclosporin (150 mg/day orally for 4 weeks) resulted in remarkable improvement in visual acuity and cure of the uveitis. All medications were discontinued, and the patient has been asymptomatic since. To our knowledge, the coexistence of uveitis and tattoo granulomas has only been reported once in the English language medical literature by Rorsman et al. [1]. According to their suggestion, tattoo granulomas and uveitis may be a special granulomatous hypersensitivity syndrome induced by cobalt [1]. As with their three cases, our patient also had no signs of systemic sarcoidosis and developed the ophthalmologic symptoms delayed after having had his skin tattooed.
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